MINDSET 2 Study:Testing a New Pill Treatment for Alzheimer's
MINDSET 2 is a phase 3 clinical trial for people with mild to moderate Alzheimer's disease. The study tests whether a new experimental pill treatment (KarXT + KarX-EC) is safe and can help with thinking and memory problems.
Study highlights
Key information about the MINDSET 2 study
- 60 to 85 years old
- Mild to moderate Alzheimer's disease
- Designated caregiver required
- Oral medication
- Study zone: Southern California + North Central Florida
Study goal and design
Evaluating KarXT + KarX-EC for cognitive impairment
This Phase 3 clinical trial conducted by Bristol-Myers is testing whether the new pill treatment (KarXT + KarX-EC) is safe and can improve memory, thinking, and daily functioning in people with mild to moderate Alzheimer's disease.
Participants will be randomly assigned to receive either the experimental treatment or a placebo, so researchers can compare the effects. These drugs are still investigational and have not yet been approved by the FDA.
Care and support
Comprehensive medical evaluations and monitoring
While contributing to research, participants receive:
- The possibility to receive the investigational study drug (KarXT + KarX-EC)
- Regular cognitive assessments and medical evaluations
- Study visits with qualified medical professionals
- Brain magnetic resonance imaging (MRI) assessments
All medical and travel costs related to the study are covered. Participants must have a designated caregiver who maintains adequate contact (around 10 hours per week or more) and is willing to attend all study visits.
Volunteer journey
A structured study process
Express your interest
Answer a questionnaire to check preliminary criteria and confirm eligibility.
Meet the study team
Take part in comprehensive cognitive assessments and medical evaluations including MMSE testing.
Begin treatment (or placebo)
Receive investigational treatment (KarXT + KarX-EC) or placebo orally at specified doses on specified days. Participation duration is 24 weeks.
Continue the study
Be monitored during regular follow-up visits with cognitive assessments and medical check-ups to evaluate treatment effects.
Ready to get involved?Join the MINDSET 2 study today.
Contribute to Alzheimer's research, support medical advancement, help others, and receive comprehensive care.